Genotypes

There are several different strains of the hepatitis C virus called ‘genotypes.’ These strains are slightly different in their genetic make-up, but similar enough to still be labelled hepatitis C. It is currently believed that there are at least 6 different genotypes of hepatitis C here in Australia, which are numbered 1, 2, 3, and so on. There are also subgroups within each genotype, which are further differentiated 1a, 1b, etc. The most common genotypes found in Australia are 1 and 3.

Studies have shown that it is possible to be infected with multiple hepatitis C genotypes. To prevent re-infection with a different genotype, it is important to practise the same blood awareness precautions as for preventing an initial infection. (Link to prevention page)

At this stage, there appears to be no evidence of any relationship between genotype and severity of liver disease. However, genotype is the most significant predictor of response to antiviral treatment.